Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | LSS | P48449 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7986420 | 1.00 | NPC1 (0.40) | NPC1OPRM1OPRD1LSSMEN1 | |
| SCHEMBL7975675 | 0.86 | MEN1 (0.36) | NPC1OPRM1OPRD1LSSMEN1 | |
| SCHEMBL7989433 | 0.79 | KDM4E (0.43) | NPC1ALDH1A1KDM4E | |
| SCHEMBL7986414 | 0.78 | MEN1 (0.40) | NPC1OPRM1OPRD1LSSMEN1 | |
| SCHEMBL7986417 | 0.78 | MEN1 (0.40) | NPC1OPRM1OPRD1LSSMEN1 | |
| SCHEMBL7987049 | 0.74 | MC4R (0.51) | LSSMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7987055 | 0.74 | MC4R (0.51) | LSSMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7975672 | 0.69 | MMP2 (0.40) | MEN1KMT2AMAPT | |
| SCHEMBL7977132 | 0.69 | MMP2 (0.40) | MEN1KMT2AMAPT | |
| SCHEMBL2343711 | 0.69 | NPC1 (0.56) | NPC1OPRM1OPRD1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001040198-A2 | MACROCYCLIC HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS ANTIMICROBIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2001-06-07 | — | — | WO | disclosed |