Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.51 |
| ▸ | LSS | P48449 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 3/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | FAP | Q12884 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987049 | 1.00 | MC4R (0.51) | MC4RLSSMMP2DPP4DPP7 | |
| SCHEMBL7986417 | 0.83 | MEN1 (0.40) | MC4RLSSMAPTALDH1A1MEN1 | |
| SCHEMBL7986414 | 0.83 | MEN1 (0.40) | MC4RLSSMAPTALDH1A1MEN1 | |
| SCHEMBL7975785 | 0.77 | MAOB (0.47) | ALDH1A1 | |
| SCHEMBL7975789 | 0.77 | MAOB (0.47) | ALDH1A1 | |
| SCHEMBL7977132 | 0.76 | MMP2 (0.40) | MMP2MAPTMEN1KMT2A | |
| SCHEMBL7975672 | 0.76 | MMP2 (0.40) | MMP2MAPTMEN1KMT2A | |
| SCHEMBL7986420 | 0.74 | NPC1 (0.40) | LSSMAPTSIGMAR1ALDH1A1MEN1 | |
| SCHEMBL7993025 | 0.74 | NPC1 (0.40) | LSSMAPTSIGMAR1ALDH1A1MEN1 | |
| SCHEMBL16131783 | 0.72 | LOXL2 (0.52) | MC4RMMP2DPP4DPP7DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001040198-A2 | MACROCYCLIC HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS ANTIMICROBIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2001-06-07 | — | — | WO | disclosed |