Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASE1 | P07998 | 1/20 | 0.62 |
| ▸ | TK1 | P04183 | 6/20 | 0.46 |
| ▸ | TK2 | O00142 | 1/20 | 0.42 |
| ▸ | TERT | O14746 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA5A | P35218 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7996664 | 0.84 | RNASE1 (0.73) | RNASE1TK1TK2 | |
| SCHEMBL9393168 | 0.80 | RNASE1 (0.56) | RNASE1TK1TK2TERTCA12 | |
| SCHEMBL7994005 | 0.78 | RNASE1 (0.66) | RNASE1TK1TK2 | |
| SCHEMBL13273339 | 0.77 | RNASE1 (0.82) | RNASE1TK1TK2 | |
| SCHEMBL21886791 | 0.77 | RNASE1 (0.82) | RNASE1TK1TK2 | |
| SCHEMBL22992340 | 0.77 | RNASE1 (0.82) | RNASE1TK1TK2 | |
| SCHEMBL9324478 | 0.77 | RNASE1 (0.82) | RNASE1TK1TK2 | |
| SCHEMBL9326675 | 0.77 | RNASE1 (0.82) | RNASE1TK1TK2 | |
| SCHEMBL30976654 | 0.77 | RNASE1 (0.82) | RNASE1TK1TK2 | |
| SCHEMBL10664373 | 0.77 | RNASE1 (0.82) | RNASE1TK1TK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6320040-B1 | PREPARING NOVEL NUCLEOSIDE OLIGOMERS BEARING PENDANT CONJUGATE GROUPS FOR INCORPORATION INTO NUCLEIC ACIDS | ISIS PHARMACEUTICALS, INC. | 2001-11-20 | — | — | US | disclosed |