Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.49 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.48 |
| ▸ | WNT3A | P56704 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | EDNRA | P25101 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7993516 | 0.86 | EDNRA (0.59) | LMNANPSR1MEN1KMT2AMAPT | |
| SCHEMBL7975875 | 0.83 | MAPK9 (0.61) | LMNAMAPK9NPSR1MEN1KMT2A | |
| SCHEMBL9309103 | 0.83 | ADRB3 (0.53) | LMNANPSR1MEN1KMT2AMAPT | |
| SCHEMBL7986653 | 0.82 | PTGS1 (0.51) | LMNAMAPK9MEN1KMT2AMAPT | |
| SCHEMBL7976072 | 0.82 | MAPK9 (0.52) | MAPK9NPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL7987319 | 0.80 | MAPK1 (0.50) | MAPK9CTNNB1WNT3AKMT2AALDH1A1 | |
| SCHEMBL7986479 | 0.80 | TAS1R3 (0.50) | MAPK9MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL7988098 | 0.78 | MAPK9 (0.49) | MAPK9MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL14698841 | 0.78 | KMT2A (0.55) | LMNAMAPK9NPSR1MEN1KMT2A | |
| SCHEMBL27396000 | 0.78 | LMNA (0.53) | LMNAMAPK9NPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207686-B1 | FOR THERAPY OF HYPERTENSION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-03-27 | — | — | US | disclosed |
| WO-1996015109-A1 | ENDOTHELIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-23 | — | — | WO | disclosed |