Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | BCL2 | P10415 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18487588 | 0.96 | FFAR4 (0.50) | FFAR4HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL20047462 | 0.86 | PPARA (0.47) | BCL2CA12CA1CA2CA9 | |
| SCHEMBL3078388 | 0.85 | STS (0.55) | CA12CA1CA2CA9CA14 | |
| SCHEMBL26282685 | 0.83 | FFAR4 (0.54) | KIF11FFAR4HDAC1HDAC8HDAC3 | |
| SCHEMBL29098422 | 0.82 | FFAR4 (0.52) | KIF11FFAR4HDAC1HDAC8HDAC3 | |
| SCHEMBL12550112 | 0.82 | BCL2 (0.54) | BCL2CA12CA1CA2CA9 | |
| SCHEMBL27802292 | 0.81 | FBP1 (0.52) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL7378889 | 0.80 | STS (0.58) | CA12CA1CA2CA9CA14 | |
| SCHEMBL19627393 | 0.79 | FFAR4 (0.52) | KIF11FFAR4HDAC1HDAC8HDAC3 | |
| SCHEMBL1952655 | 0.79 | MMP1 (0.48) | HDAC1HDAC8HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288261-B1 | DRUGS FOR INHIBITION OF ENZYMES | ABBOTT LABORATORIES | 2001-09-11 | — | — | US | disclosed |