Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.84 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.84 |
| ▸ | MEN1 | O00255 | 1/20 | 0.84 |
| ▸ | POLB | P06746 | 1/20 | 0.84 |
| ▸ | XBP1 | P17861 | 1/20 | 0.84 |
| ▸ | ESR1 | P03372 | 5/20 | 0.70 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.70 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.70 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.70 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.70 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.70 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.70 |
| ▸ | MAOA | P21397 | 1/20 | 0.70 |
| ▸ | PDE5A | O76074 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | ATM | Q13315 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.64 |
| ▸ | SLC2A9 | Q9NRM0 | 2/20 | 0.64 |
| ▸ | XDH | P47989 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8175342 | 0.91 | MAPT (0.84) | MAPTKMT2AMEN1POLBXBP1 | |
| SCHEMBL30766285 | 0.91 | MAPT (0.84) | MAPTKMT2AMEN1POLBXBP1 | |
| SCHEMBL8002908 | 0.91 | MAPT (0.84) | MAPTKMT2AMEN1POLBXBP1 | |
| Lonchocarpol A SCHEMBL31091681 | 0.91 | MAPT (1.00) | MAPTKMT2AMEN1POLBXBP1 | |
| Lonchocarpol A SCHEMBL144277 | 0.91 | MAPT (1.00) | MAPTKMT2AMEN1POLBXBP1 | |
| Lonchocarpol A SCHEMBL144276 | 0.91 | MAPT (1.00) | MAPTKMT2AMEN1POLBXBP1 | |
| SCHEMBL17738789 | 0.88 | KMT2A (0.65) | MAPTKMT2AMEN1POLBXBP1 | |
| SCHEMBL24075554 | 0.82 | MAPT (0.83) | MAPTKMT2AMEN1POLBXBP1 | |
| Sophoraflavanone B SCHEMBL14304885 | 0.82 | ESR1 (1.00) | MAPTKMT2AMEN1POLBXBP1 | |
| Sophoraflavanone B SCHEMBL1171435 | 0.82 | ESR1 (1.00) | MAPTKMT2AMEN1POLBXBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6136849-A | PURITY; PLANT EXTRACT | HOFFMANN JOSEPH J (US) | 2000-10-24 | — | — | US | claimed |
| US-6136849-A | PURITY; PLANT EXTRACT | HOFFMANN JOSEPH J (US) | 2000-10-24 | — | — | US | disclosed |
| US-6136849-A | PURITY; PLANT EXTRACT | HOFFMANN JOSEPH J (US) | 2000-10-24 | — | — | US | disclosed |
| WO-2000020406-A1 | ANTIBACTERIAL AND ANTIFUNGAL FLAVANONES FROM $i(EYSENHARDTIA TEXANA) | RESEARCH DEVELOPMENT FOUNDATION (US) | 2000-04-13 | — | — | WO | disclosed |
| WO-2000020406-A1 | ANTIBACTERIAL AND ANTIFUNGAL FLAVANONES FROM $i(EYSENHARDTIA TEXANA) | RESEARCH DEVELOPMENT FOUNDATION (US) | 2000-04-13 | — | — | WO | disclosed |