Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.84 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.84 |
| ▸ | MEN1 | O00255 | 1/20 | 0.84 |
| ▸ | POLB | P06746 | 1/20 | 0.84 |
| ▸ | XBP1 | P17861 | 1/20 | 0.84 |
| ▸ | ESR1 | P03372 | 5/20 | 0.73 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.73 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.73 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.73 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.73 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.73 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.73 |
| ▸ | MAOA | P21397 | 1/20 | 0.73 |
| ▸ | PDE5A | O76074 | 1/20 | 0.73 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.66 |
| ▸ | PRKCA | P17252 | 1/20 | 0.66 |
| ▸ | BACE1 | P56817 | 1/20 | 0.66 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8002908 | 1.00 | MAPT (0.84) | MAPTKMT2AMEN1POLBXBP1 | |
| SCHEMBL30766285 | 1.00 | MAPT (0.84) | MAPTKMT2AMEN1POLBXBP1 | |
| SCHEMBL7993201 | 0.91 | MAPT (0.84) | MAPTKMT2AMEN1POLBXBP1 | |
| Lonchocarpol A SCHEMBL144277 | 0.91 | MAPT (1.00) | MAPTKMT2AMEN1POLBXBP1 | |
| Lonchocarpol A SCHEMBL144276 | 0.91 | MAPT (1.00) | MAPTKMT2AMEN1POLBXBP1 | |
| Lonchocarpol A SCHEMBL31091681 | 0.91 | MAPT (1.00) | MAPTKMT2AMEN1POLBXBP1 | |
| Sophoraflavanone B SCHEMBL1171435 | 0.84 | ESR1 (1.00) | MAPTKMT2AMEN1POLBXBP1 | |
| Sophoraflavanone B SCHEMBL29396586 | 0.84 | ESR1 (1.00) | MAPTKMT2AMEN1POLBXBP1 | |
| Sophoraflavanone B SCHEMBL14304885 | 0.84 | ESR1 (1.00) | MAPTKMT2AMEN1POLBXBP1 | |
| Sophoraflavanone B SCHEMBL147316 | 0.84 | ESR1 (1.00) | MAPTKMT2AMEN1POLBXBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6136849-A | PURITY; PLANT EXTRACT | HOFFMANN JOSEPH J (US) | 2000-10-24 | — | — | US | disclosed |