Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1403152 | 0.92 | BACE1 (0.40) | BACE1MAPTSMN1; SMN2GAANPSR1 | |
| SCHEMBL1403176 | 0.92 | BACE1 (0.40) | BACE1MAPTSMN1; SMN2GAA | |
| SCHEMBL7992161 | 0.91 | BACE1 (0.39) | BACE1MAPTSMN1; SMN2GAANPSR1 | |
| SCHEMBL695478 | 0.89 | BACE1 (0.38) | BACE1 | |
| SCHEMBL16701732 | 0.88 | GABRA1 (0.38) | BACE1 | |
| SCHEMBL16197279 | 0.84 | MAPT (0.37) | BACE1MAPTSMN1; SMN2GAA | |
| SCHEMBL16701535 | 0.82 | BACE1 (0.37) | BACE1MAPTSMN1; SMN2GAA | |
| SCHEMBL1018668 | 0.82 | BACE1 (0.41) | BACE1 | |
| SCHEMBL20564470 | 0.81 | DEGS1 (0.43) | BACE1MAPTSMN1; SMN2 | |
| SCHEMBL1014697 | 0.80 | BACE1 (0.38) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113402436-B | Tertiary amino acid derivative, preparation method and application thereof | 安徽农业大学 | 2024-07-12 | — | — | CN | disclosed |
| CN-113582904-B | 5-n-propyl-4-hydroxypyrrole-2-ketone derivative and preparation method and application thereof | 安徽农业大学 | 2023-03-10 | — | — | CN | disclosed |
| CN-113582904-A | 5-n-propyl-4-hydroxypyrrole-2-ketone derivative and preparation method and application thereof | 安徽农业大学 | 2021-11-02 | — | — | CN | disclosed |
| CN-113402436-A | Trolamine derivatives, preparation method and application thereof | 安徽农业大学 | 2021-09-17 | — | — | CN | disclosed |
| CN-112778188-A | Preparation method of alternaria tenuifolia keto acid and derivatives thereof | 安徽农业大学 | 2021-05-11 | — | — | CN | disclosed |
| WO-2001017977-A1 | 1,3,5-TRIAZINES AS HERBICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 2001-03-15 | — | — | WO | disclosed |
| US-5859283-A | TERTIARY-BUTYL 3-CYCLOALKYL-3-OXOPROPIONATE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-12 | — | — | US | disclosed |
| US-5747424-A | HEATING AN AROMATIC DIKETONE WITH A SALT OF HYDROXYLAMINE IN A SOLVENT | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-05-05 | — | — | US | disclosed |
| US-5656573-A | Herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-12 | — | — | US | disclosed |
| US-5650533-A | Intermediates to herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-07-22 | — | — | US | disclosed |
| EP-0418175-B1 | Isoxazoles herbicides | RHONE POULENC AGRICULTURE (GB) | 1996-07-17 | — | — | EP | disclosed |
| EP-0470856-B1 | Isoxazole derivatives, process for their preparation and their herbicidal applications | RHONE POULENC AGRICULTURE (GB) | 1995-10-11 | — | — | EP | disclosed |
| EP-0470856-A1 | Isoxazole derivatives, process for their preparation and their herbicidal applications | RHONE-POULENC AGRICULTURE LTD. (GB) | 1992-02-12 | — | — | EP | disclosed |
| WO-1991011448-A1 | THERAPEUTIC AGENTS | THE BOOTS COMPANY PLC (GB) | 1991-08-08 | — | — | WO | disclosed |
| EP-0418175-A2 | Isoxazoles herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1991-03-20 | — | — | EP | disclosed |