Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 2/20 | 0.41 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.39 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21614225 | 0.78 | MAPT (0.45) | MAPTKDM4EALDH1A1GAAHPGD | |
| Ammonia Solution, Strong SCHEMBL28474104 | 0.76 | MAPT (0.44) | MAPTKDM4EALDH1A1GAAHPGD | |
| SCHEMBL8404448 | 0.74 | GPR3 (0.59) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL27764235 | 0.72 | GPR3 (0.56) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL5478388 | 0.72 | GPR3 (0.64) | MAPTKDM4EALDH1A1GAAHPGD | |
| SCHEMBL7695464 | 0.71 | NQO2 (0.62) | MAPTKDM4EALDH1A1GAAHPGD | |
| SCHEMBL1976533 | 0.70 | CYP2A6 (0.50) | MAPTKDM4EALDH1A1GAAHPGD | |
| SCHEMBL4642683 | 0.70 | CYP2A6 (0.50) | MAPTKDM4EALDH1A1GAAHPGD | |
| SCHEMBL29853846 | 0.70 | CYP2A6 (0.50) | MAPTKDM4EALDH1A1GAAHPGD | |
| SCHEMBL17532730 | 0.69 | MAPT (0.52) | MAPTKDM4EALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017997-A1 | SUBSTITUTED DIAZAANTHRACENE COMPOUNDS HAVING PHARMACEUTICAL UTILITY | DIAZANS LIMITED (CA) | 2001-03-15 | — | — | WO | disclosed |
| US-5994365-A | BACTERICIDES; FUNGICIDES; ANTITUMOR AGENT | DIAZANS LIMITED (CA) | 1999-11-30 | — | — | US | disclosed |