SCHEMBL5478388

SCHEMBL5478388

c1ccc2cc3c(cc2c1)nnc1ccccc13

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 3/20 0.64
NQO2 P16083 2/20 0.52
ESR1 P03372 2/20 0.50
ESR2 Q92731 2/20 0.50
KDM4E B2RXH2 5/20 0.45
PI4KA P42356 1/20 0.42
PI4K2B Q8TCG2 1/20 0.42
PI4K2A Q9BTU6 1/20 0.42
PI4KB Q9UBF8 1/20 0.42
ALDH1A1 P00352 5/20 0.42
GLA P06280 4/20 0.42
HPGD P15428 4/20 0.42
MAPT P10636 3/20 0.42
ACHE P22303 2/20 0.42
HSD17B10 Q99714 2/20 0.41
HIF1A Q16665 1/20 0.41
CYP1B1 Q16678 1/20 0.41
CLK1 P49759 1/20 0.40
RAD52 P43351 1/20 0.40
SMARCA2 P51531 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4506468 0.84 ESR1 (0.68) GPR3NQO2ESR1ESR2KDM4E
Benzonaphthyridine SCHEMBL29600756 0.80 GPR3 (1.00) GPR3NQO2KDM4EALDH1A1GLA
Benzonaphthyridine SCHEMBL30897319 0.80 GPR3 (1.00) GPR3NQO2KDM4EALDH1A1GLA
Benzonaphthyridine SCHEMBL51197 0.80 GPR3 (1.00) GPR3NQO2KDM4EALDH1A1GLA
SCHEMBL4485428 0.74 GPR3 (0.87) GPR3NQO2KDM4EALDH1A1GLA
SCHEMBL7993295 0.72 MAPT (0.46) GPR3NQO2ESR1ESR2KDM4E
SCHEMBL11517561 0.71 GPR3 (0.61) GPR3KDM4EALDH1A1HPGDMAPT
SCHEMBL11196099 0.71 GPR3 (0.61) GPR3ESR1ESR2KDM4EALDH1A1
SCHEMBL14627008 0.71 GPR3 (0.61) GPR3NQO2KDM4EALDH1A1MAPT
SCHEMBL14612005 0.71 GPR3 (0.61) GPR3NQO2KDM4EALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7183010-B2 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK CORPORATION (US) 2007-02-27 US disclosed
US-20040076853-A1 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK COMPANY 2004-04-22 US disclosed