Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | DDX3X | O00571 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4266561 | 0.83 | ME2 (0.34) | KDM4EMEN1KMT2ANPC1TP53 | |
| SCHEMBL7258049 | 0.80 | MAPT (0.40) | HSP90AA1MEN1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL7257337 | 0.78 | TDP1 (0.40) | KDM4EMEN1ALDH1A1KMT2ANPC1 | |
| SCHEMBL28890813 | 0.76 | BACE1 (0.38) | KDM4EGABRG2GABRB3GABRA3GABRA1 | |
| SCHEMBL7261873 | 0.75 | MAPT (0.38) | KDM4ECYP1A2MEN1ALDH1A1KMT2A | |
| SCHEMBL7261530 | 0.73 | ALDH1A1 (0.35) | KDM4ECYP1A2CYP2D6CYP2C19HSP90AA1 | |
| SCHEMBL585529 | 0.72 | CLK4 (0.39) | KDM4ECYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL6804334 | 0.71 | CYP1A1 (0.33) | KDM4ECYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL28353822 | 0.71 | TSHR (0.31) | SLC6A3KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL29163406 | 0.71 | NPC1 (0.38) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001074818-A1 | CHLORINS WITH FUSED RINGS FOR USE IN PHOTODYNAMIC THERAPY | MIRAVANT PHARMACEUTICALS, INC. (US) | 2001-10-11 | — | — | WO | disclosed |