Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 4/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 9/20 | 0.37 |
| ▸ | BCL2 | P10415 | 5/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 4/20 | 0.37 |
| ▸ | BAD | Q92934 | 2/20 | 0.36 |
| ▸ | MRE11 | P49959 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7594254 | 0.84 | CYP3A4 (0.34) | MMP3MCL1ALDH1A1KDM4EHPGD | |
| SCHEMBL7395958 | 0.82 | TSHR (0.34) | ALDH1A1KDM4EMEN1CYP1A2HPGD | |
| SCHEMBL7996980 | 0.72 | MMP3 (0.69) | MMP3MCL1 | |
| SCHEMBL3223372 | 0.70 | BID (0.50) | MCL1BCL2L1ALDH1A1KDM4EMEN1 | |
| SCHEMBL16038801 | 0.70 | CYP1A2 (0.47) | MMP3MCL1BCL2L1ALDH1A1KDM4E | |
| SCHEMBL9256709 | 0.69 | BID (0.56) | MCL1BCL2L1ALDH1A1KDM4EMEN1 | |
| Ammonia Solution, Strong SCHEMBL7713405 | 0.69 | BID (0.49) | MCL1BCL2L1ALDH1A1KDM4EMEN1 | |
| Ammonia Solution, Strong SCHEMBL7713404 | 0.69 | BID (0.49) | MCL1BCL2L1ALDH1A1KDM4EMEN1 | |
| SCHEMBL7184885 | 0.68 | BID (0.58) | MCL1BCL2L1KDM4EHSD17B10 | |
| SCHEMBL11342368 | 0.68 | BID (0.58) | MCL1BCL2L1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288261-B1 | DRUGS FOR INHIBITION OF ENZYMES | ABBOTT LABORATORIES | 2001-09-11 | — | — | US | disclosed |