Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.65 |
| ▸ | DRD4 | P21917 | 2/20 | 0.65 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 3/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9297541 | 0.87 | HTR2A (0.61) | HTR2ADRD4ADRA1AMAPTHTR1A | |
| SCHEMBL7993422 | 0.82 | HTR2A (0.74) | HTR2ADRD4ADRA1AMAPTHTR1A | |
| SCHEMBL7679404 | 0.79 | DRD4 (1.00) | HTR2ADRD4ADRA1AMAPT | |
| SCHEMBL7815509 | 0.77 | HTR2A (0.61) | HTR2ADRD4ADRA1AMAPTHTR1A | |
| Maleic Acid SCHEMBL7993854 | 0.77 | HTR2A (0.66) | HTR2ADRD4ADRA1AMAPTHTR1A | |
| Fumaric Acid SCHEMBL7993860 | 0.77 | HTR2A (0.66) | HTR2ADRD4ADRA1AMAPTHTR1A | |
| SCHEMBL8651520 | 0.76 | HTR2A (0.59) | HTR2ADRD4ADRA1AMAPTHTR1A | |
| SCHEMBL7817436 | 0.75 | HTR2A (0.56) | HTR2ADRD4ADRA1AMAPTHTR1A | |
| SCHEMBL4442569 | 0.75 | HTR1A (0.65) | HTR2ADRD4ADRA1AHTR1ADRD2 | |
| SCHEMBL7996802 | 0.75 | HTR2A (0.73) | HTR2ADRD4ADRA1AMAPTHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284775-B1 | PSYCHOLOGICAL DISORDERS | AVENTIS PHARMACEUTICALS INC. | 2001-09-04 | — | — | US | disclosed |
| US-5801186-A | ANTIPSYCHOTIC AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1998-09-01 | — | — | US | disclosed |
| US-5371087-A | Antipsychotic, analgesics, anticonvulsant and anxiolytic agent | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1994-12-06 | — | — | US | disclosed |
| US-5229388-A | 3-[4-(1-substituted-4-piperazinyl)butyl]-4-thiazolidinone and related compounds | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-07-20 | — | — | US | disclosed |