SCHEMBL7993623

SCHEMBL7993623

NC(=O)C[C@H](N)C(=O)OC=O

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.31
BLM P54132 1/20 0.31
PMP22 Q01453 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9614483 0.83 GRIK1 (0.30)
SCHEMBL30874220 0.83 GABRR1 (0.38)
SCHEMBL10795799 0.81 ALDH1A1 (0.36)
SCHEMBL15391928 0.79 ALOX15 (0.52) ALOX15BLMPMP22KMT2A
SCHEMBL1064390 0.77
SCHEMBL3134815 0.77 SLC7A5 (0.50)
SCHEMBL995487 0.77 ALOX15 (0.36) ALOX15BLMPMP22KMT2A
SCHEMBL11061010 0.77 ALOX15 (0.36) ALOX15BLMPMP22KMT2A
SCHEMBL9674473 0.76
SCHEMBL1045518 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023064458-A1 SELECTIVE JAK2 INHIBITORS AND METHODS OF USE YALE UNIVERSITY (US) 2023-04-20 WO disclosed
EP-0854934-A4 DETECTION OF ORGANIC COMPOUNDS THROUGH REGULATION OF ANTIBODY-CATALYZED REACTIONS LANDRY DONALD W (US) 2000-09-06 EP disclosed
WO-1998049186-A1 DIPEPTIDE SURROGATES CONTAINING ASPARAGINE-DERIVED TETRAHYDROPYRIMIDINONES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1998-11-05 WO disclosed
EP-0854934-A1 DETECTION OF ORGANIC COMPOUNDS THROUGH REGULATION OF ANTIBODY-CATALYZED REACTIONS Landry, Donald W. (US) 1998-07-29 EP disclosed
US-5736343-A BIOCHEMICAL IMMOBILIZATION LANDRY DONALD (US) 1998-04-07 US disclosed
WO-1997007236-A1 DETECTION OF ORGANIC COMPOUNDS THROUGH REGULATION OF ANTIBODY-CATALYZED REACTIONS LANDRY DONALD W (US) 1997-02-27 WO disclosed
US-4745124-A THIO/ESTER PEPTIDES UNIVERSITY OF MIAMI (US) 1988-05-17 US disclosed
US-4734420-A INHIBITORS OF ANGIOTENSIN CONVERTING ENZYME UNIVERSITY OF MIAMI (US) 1988-03-29 US disclosed