Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 14/20 | 0.41 |
| ▸ | MMP3 | P08254 | 6/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7986075 | 0.86 | ALDH1A1 (0.46) | ALDH1A1RECQLKMT2A | |
| SCHEMBL7986078 | 0.86 | ALDH1A1 (0.46) | ALDH1A1RECQLKMT2A | |
| SCHEMBL7993721 | 0.83 | ALDH1A1 (0.40) | MMP2MMP3MMP12ALDH1A1RECQL | |
| SCHEMBL7989742 | 0.77 | RECQL (0.45) | ALDH1A1RECQLKMT2A | |
| SCHEMBL7989744 | 0.77 | RECQL (0.45) | ALDH1A1RECQLKMT2A | |
| SCHEMBL7989849 | 0.77 | PDF (0.37) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL7976169 | 0.76 | PDF (0.44) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL7977102 | 0.76 | PDF (0.44) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL7992880 | 0.75 | PDF (0.40) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL7995047 | 0.73 | PDF (0.43) | MMP2MMP3MMP1MMP9MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001040198-A2 | MACROCYCLIC HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS ANTIMICROBIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2001-06-07 | — | — | WO | disclosed |