Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT2 | O60551 | 4/20 | 0.41 |
| ▸ | NMT1 | P30419 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7994068 | 0.76 | KDM4E (0.33) | MAPK1KDM4EMAPT | |
| SCHEMBL23748726 | 0.75 | TSHR (0.60) | TSHRHSD17B10TP53MAPK1KDM4E | |
| SCHEMBL16674486 | 0.75 | TSHR (0.51) | TSHRTBXAS1HSD17B10USP2TP53 | |
| SCHEMBL30689715 | 0.73 | ALDH1A1 (0.60) | TSHRHSD17B10RECQLKDM4EALDH1A1 | |
| SCHEMBL24864131 | 0.72 | TDP1 (0.42) | NMT2NMT1ADRB2ADRB1ADRB3 | |
| SCHEMBL13125232 | 0.72 | CA12 (0.43) | ALDH1A1CYP1A2HPGD | |
| SCHEMBL14461315 | 0.72 | RXFP1 (0.50) | TSHRHSD17B10MAPK1MRGPRX4KDM4E | |
| SCHEMBL7997530 | 0.71 | CA12 (0.57) | TSHRHSD17B10MRGPRX4KDM4EPDK2 | |
| SCHEMBL12634927 | 0.71 | MAPT (0.45) | NMT2NMT1USP2MAPK1KDM4E | |
| SCHEMBL14967158 | 0.71 | IDO1 (0.39) | TSHRHSD17B10TP53KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |