Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | DUT | P33316 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4295990 | 0.84 | KDM4E (0.46) | KDM4EMAPK1L3MBTL1DUTMAPT | |
| SCHEMBL7963933 | 0.82 | KDM4E (0.40) | KDM4EMAPK1L3MBTL1DUTMAPT | |
| SCHEMBL14461313 | 0.81 | RXFP1 (0.40) | KDM4EMAPK1L3MBTL1MAPTNPSR1 | |
| SCHEMBL16955786 | 0.79 | L3MBTL1 (0.38) | KDM4EL3MBTL1MAPTNPSR1 | |
| SCHEMBL7994096 | 0.76 | NMT2 (0.41) | KDM4EMAPK1MAPT | |
| SCHEMBL16955194 | 0.76 | L3MBTL1 (0.42) | MAPK1L3MBTL1MAPTNPSR1 | |
| SCHEMBL12634752 | 0.76 | MAPT (0.40) | KDM4EMAPK1L3MBTL1DUTMAPT | |
| SCHEMBL20294518 | 0.74 | KDM4E (0.41) | KDM4EMAPK1L3MBTL1DUTMAPT | |
| SCHEMBL13117518 | 0.74 | CD274 (0.40) | KDM4EMAPK1DUT | |
| SCHEMBL17243934 | 0.72 | ELANE (0.39) | KDM4EMAPK1L3MBTL1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |