Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 7/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 7/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.31 |
| ▸ | APLNR | P35414 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3864729 | 0.83 | DDB1 (0.37) | SRD5A2DDB1CRBNHSD11B1 | |
| SCHEMBL16320941 | 0.69 | SLC1A2 (0.33) | SLC1A2SLC1A1HTTAPLNR | |
| SCHEMBL6350703 | 0.67 | SLC1A2 (0.37) | SLC1A2SLC1A1HSD11B1APLNR | |
| SCHEMBL2017042 | 0.67 | SLC1A2 (0.34) | SLC1A2SLC1A1HTTHSD11B1APLNR | |
| SCHEMBL2017466 | 0.67 | SLC1A2 (0.34) | SLC1A2SLC1A1HTTHSD11B1APLNR | |
| SCHEMBL2019347 | 0.65 | HSD11B1 (0.33) | SLC1A2SLC1A1HSD11B1APLNR | |
| SCHEMBL27488807 | 0.65 | HTT (0.33) | HTTAPLNR | |
| SCHEMBL8183184 | 0.64 | SLC1A2 (0.43) | SLC1A2SLC1A1HSD11B1APLNR | |
| SCHEMBL25117220 | 0.62 | SLC1A2 (0.43) | SLC1A2SLC1A1HSD11B1APLNR | |
| SCHEMBL23662945 | 0.62 | SLC1A2 (0.43) | SLC1A2SLC1A1HSD11B1APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000025782-A1 | DIHYDROPYRIDINONES AND PYRROLINONES USEFUL AS ALPHA 1A ADRENOCEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 2000-05-11 | — | — | WO | disclosed |