Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | FNTA | P49354 | 7/20 | 0.49 |
| ▸ | FNTB | P49356 | 7/20 | 0.49 |
| ▸ | PGGT1B | P53609 | 7/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7995820 | 0.78 | ALDH1A1 (0.62) | NPC1POLBFNTAFNTBPGGT1B | |
| SCHEMBL22274826 | 0.76 | NPSR1 (0.67) | NPSR1NPC1TP53TSHRRAB9A | |
| SCHEMBL10944776 | 0.73 | NPC1 (0.60) | NPC1POLBFNTAFNTBPGGT1B | |
| SCHEMBL10943971 | 0.73 | ALDH1A1 (0.55) | NPC1POLBFNTAFNTBPGGT1B | |
| SCHEMBL11008794 | 0.73 | ALDH1A1 (0.67) | NPC1POLBALDH1A1 | |
| SCHEMBL11009648 | 0.73 | ALDH1A1 (0.60) | NPC1POLBFNTAFNTBPGGT1B | |
| SCHEMBL11009515 | 0.72 | ALDH1A1 (0.62) | NPC1POLBFNTAFNTBPGGT1B | |
| SCHEMBL11011312 | 0.72 | ALDH1A1 (0.58) | NPC1POLBFNTAFNTBPGGT1B | |
| SCHEMBL13979988 | 0.71 | NPSR1 (0.59) | NPSR1NPC1POLBRAB9AALDH1A1 | |
| SCHEMBL10942842 | 0.70 | ALDH1A1 (0.65) | NPC1POLBFNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |