Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | MTOR | P42345 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | GMNN | O75496 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27460294 | 0.80 | ALDH1A1 (0.69) | ALDH1A1FNTAFNTBPGGT1BNPC1 | |
| SCHEMBL10942842 | 0.80 | ALDH1A1 (0.65) | ALDH1A1CYP1A2CYP2C9MEN1KMT2A | |
| SCHEMBL10944776 | 0.80 | NPC1 (0.60) | ALDH1A1MEN1KMT2AFNTAFNTB | |
| SCHEMBL7994244 | 0.78 | NPSR1 (0.58) | ALDH1A1TP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3807868 | 0.78 | ALDH1A1 (0.97) | ALDH1A1MEN1KMT2AFNTAFNTB | |
| SCHEMBL6328193 | 0.77 | TBXAS1 (0.66) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL16797086 | 0.76 | CYP11B1 (0.60) | ALDH1A1FNTAFNTBPGGT1BCYP19A1 | |
| SCHEMBL11008794 | 0.76 | ALDH1A1 (0.67) | ALDH1A1NPC1POLBCYP19A1 | |
| SCHEMBL11009648 | 0.76 | ALDH1A1 (0.60) | ALDH1A1FNTAFNTBPGGT1BNPC1 | |
| SCHEMBL2719783 | 0.76 | CYP11B1 (0.72) | CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |