Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 5/20 | 0.40 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.39 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7990886 | 0.90 | KCNH2 (0.53) | KCNH2HRH1MCHR1CHRM2CHRM1 | |
| SCHEMBL7976548 | 0.86 | KCNH2 (0.46) | KCNH2HRH1CHRM2CHRM1FAAH | |
| SCHEMBL7470197 | 0.85 | KCNH2 (0.61) | KCNH2HRH1MCHR1DNMT1EHMT2 | |
| SCHEMBL7990925 | 0.84 | KCNH2 (0.45) | KCNH2HRH1CHRM2CHRM1FAAH | |
| SCHEMBL7990602 | 0.78 | KCNH2 (0.45) | KCNH2HRH1MCHR1CHRM2CHRM1 | |
| SCHEMBL7976493 | 0.77 | KCNH2 (0.45) | KCNH2HRH1DNMT1EHMT2DRD4 | |
| SCHEMBL7469624 | 0.73 | KCNH2 (0.61) | KCNH2HRH1DNMT1EHMT2DRD4 | |
| SCHEMBL7467030 | 0.71 | DNMT1 (0.53) | KCNH2HRH1DNMT1EHMT2 | |
| SCHEMBL10735878 | 0.68 | KCNH2 (0.63) | KCNH2HRH1DRD4 | |
| SCHEMBL6362147 | 0.68 | KCNH2 (0.83) | KCNH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6184234-B1 | EFFECTIVE AGRICULTURAL PESTICIDE FOR TOBACCO, BEETS, BEANS, CABBAGE CROPS | FMC CORPORATION | 2001-02-06 | — | — | US | claimed |