Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13601262 | 0.88 | BACE1 (0.36) | BACE1 | |
| SCHEMBL13601255 | 0.82 | BACE1 (0.36) | BACE1 | |
| SCHEMBL4508013 | 0.82 | BACE1 (0.32) | BACE1 | |
| SCHEMBL8004956 | 0.82 | BACE1 (0.35) | BACE1 | |
| SCHEMBL7992575 | 0.81 | BACE1 (0.38) | BACE1 | |
| SCHEMBL8005030 | 0.81 | REN (0.32) | BACE1 | |
| SCHEMBL8004960 | 0.80 | CTSD (0.31) | — | |
| SCHEMBL8009577 | 0.80 | CTSD (0.31) | — | |
| SCHEMBL13601253 | 0.80 | CTSD (0.31) | — | |
| SCHEMBL4517448 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106599-A2 | SUBSTITUTED PIPERIDINES AS THERAPEUTIC COMPOUNDS | NOVARTIS AG (CH) | 2009-09-03 | — | — | WO | disclosed |
| WO-2007141318-A1 | 2,5-DISUBSTITUTED PIPERIDINES | SPEEDEL EXPERIMENTA AG (CH) | 2007-12-13 | — | — | WO | disclosed |