Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.35 |
| ▸ | VDR | P11473 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4392043 | 0.79 | KMT2A (0.40) | KMT2ASMPD1PLA2G4BLTB4RESR1 | |
| Trifluoroacetic Acid SCHEMBL4392038 | 0.79 | KMT2A (0.40) | KMT2ASMPD1PLA2G4BLTB4RESR1 | |
| SCHEMBL4379354 | 0.75 | KMT2A (0.39) | KMT2ASMPD1ESR1 | |
| SCHEMBL4379352 | 0.75 | KMT2A (0.39) | KMT2ASMPD1ESR1 | |
| SCHEMBL4378007 | 0.73 | KMT2A (0.48) | KMT2ASMPD1MEN1ALDH1A1 | |
| SCHEMBL7990787 | 0.73 | MCL1 (0.48) | KMT2AMEN1ALDH1A1HTTPOLB | |
| SCHEMBL7988340 | 0.69 | CYP2D6 (0.52) | ALDH1A1HTT | |
| SCHEMBL8794357 | 0.66 | MAOB (0.47) | KMT2AMEN1TSHRMAPK1ALDH1A1 | |
| SCHEMBL4383633 | 0.65 | KMT2A (0.45) | KMT2ASMPD1PLA2G4BTSHRMAPK1 | |
| SCHEMBL4379687 | 0.62 | KMT2A (0.50) | KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | disclosed |