Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7994747 | 0.80 | KDM4E (0.45) | KMT2AKDM4EALDH1A1GAAUSP2 | |
| SCHEMBL4378007 | 0.78 | KMT2A (0.48) | KMT2AALDH1A1MEN1 | |
| Oxalic Acid SCHEMBL7990786 | 0.76 | KDM4E (0.52) | MCL1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL4385045 | 0.75 | L3MBTL1 (0.47) | MCL1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL7989029 | 0.73 | ATM (0.39) | KDM4EALDH1A1GAAL3MBTL1POLB | |
| SCHEMBL7994443 | 0.73 | KMT2A (0.36) | KMT2AALDH1A1HTTMEN1POLB | |
| SCHEMBL8794637 | 0.72 | ENPP2 (0.42) | MCL1KDM4EALDH1A1GAAUSP2 | |
| SCHEMBL16234239 | 0.72 | MCL1 (0.47) | MCL1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL4385050 | 0.72 | LMNA (0.48) | MCL1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL11860150 | 0.70 | PRSS1 (0.55) | KDM4EFAAHMRGPRX4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | disclosed |