Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 4/20 | 0.36 |
| ▸ | CES1 | P23141 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.33 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30846979 | 1.00 | PAOX (0.48) | PAOXALDH1A1ACHECES2CES1 | |
| SCHEMBL11401257 | 1.00 | PAOX (0.48) | PAOXALDH1A1ACHECES2CES1 | |
| SCHEMBL6279788 | 0.91 | — | — | |
| SCHEMBL426087 | 0.82 | TSHR (0.55) | ALDH1A1LMNAGGPS1TSHRNFKB1 | |
| SCHEMBL8070797 | 0.82 | TSHR (0.55) | ALDH1A1LMNAGGPS1TSHRNFKB1 | |
| SCHEMBL373838 | 0.80 | EPHX2 (0.39) | PAOXALDH1A1 | |
| SCHEMBL1169405 | 0.80 | — | — | |
| SCHEMBL16723870 | 0.77 | PAOX (0.72) | PAOXALDH1A1ACHECES2CES1 | |
| SCHEMBL21818217 | 0.77 | PAOX (0.72) | PAOXALDH1A1ACHECES2CES1 | |
| SCHEMBL8421741 | 0.77 | PAOX (0.72) | PAOXALDH1A1ACHECES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001051481-A1 | METHOD FOR THE SYNTHESIS OF 6N-PENTYL-2H-PYRAN-2-ONE | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2001-07-19 | — | — | WO | disclosed |