Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.50 |
| ▸ | PPARG | P37231 | 7/20 | 0.50 |
| ▸ | PPARD | Q03181 | 7/20 | 0.50 |
| ▸ | PPARA | Q07869 | 7/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8070797 | 1.00 | TSHR (0.55) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL15467127 | 0.91 | — | — | |
| SCHEMBL3192362 | 0.89 | PPARG (0.59) | TSHRLMNAPPARGPPARDPPARA | |
| SCHEMBL8592585 | 0.88 | LMNA (0.46) | TSHRLMNANFKB1PMP22GPR84 | |
| Octanedioate SCHEMBL5321589 | 0.85 | TSHR (0.67) | TSHRLMNANFKB1PMP22GPR84 | |
| Adipic Acid SCHEMBL11412900 | 0.83 | LMNA (0.65) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL11401257 | 0.82 | PAOX (0.48) | TSHRLMNANFKB1PMP22ALDH1A1 | |
| SCHEMBL7994585 | 0.82 | PAOX (0.48) | TSHRLMNANFKB1PMP22ALDH1A1 | |
| SCHEMBL9635507 | 0.81 | TSHR (0.60) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL2581538 | 0.81 | TSHR (0.60) | TSHRLMNANFKB1PMP22GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170233400-A1 | METHODS FOR MAKING 3-O-PROTECTED MORPHINONES AND 3-O-PROTECTED MORPHINONE DIENOL CARBOXYLATES | EURO-CELTIQUE S.A. (LU) | 2017-08-17 | — | — | US | disclosed |
| US-9670218-B2 | Methods for making 3-O-protected morphinones and 3-O-protected morphinone dienol carboxylates | PURDUE PHARMA L.P. (US) | 2017-06-06 | — | — | US | disclosed |
| US-20150239898-A1 | METHODS FOR MAKING 3-O-PROTECTED MORPHINONES AND 3-O-PROTECTED MORPHINONE DIENOL CARBOXYLATES | EURO-CELTIQUE S.A. (LU) | 2015-08-27 | — | — | US | disclosed |
| US-8975257-B2 | Methods for making 3-O-protected morphinones and 3-O-protected morphinone dienol carboxylates | PURDUE PHARMA L.P. (US) | 2015-03-10 | — | — | US | disclosed |
| US-20140171643-A1 | METHODS FOR MAKING 3-O-PROTECTED MORPHINONES AND 3-O-PROTECTED MORPHINONE DIENOL CARBOXYLATES | PURDUE PHARMA L.P. (US) | 2014-06-19 | — | — | US | disclosed |
| US-20120225902-A1 | METHODS FOR MAKING 3-O-PROTECTED MORPHINONES AND 3-O-PROTECTED MORPHINONE DIENOL CARBOXYLATES | PURDUE PHARMA L.P. (US) | 2012-09-06 | — | — | US | disclosed |
| US-8198444-B2 | Methods for making 3-O-protected morphinones and 3-O-protected morphinone dienol carboxylates | PURDUE PHARMA L.P. (US) | 2012-06-12 | — | — | US | disclosed |
| US-20120022259-A1 | METHODS FOR MAKING 3-O-PROTECTED MORPHINONES AND 3-O-PROTECTED MORPHINONE DIENOL CARBOXYLATES | PURDUE PHARMA L.P. (US) | 2012-01-26 | — | — | US | disclosed |
| EP-2035442-B1 | NEW SUPPORTED OXIDATION REACTANTS, PROCESS FOR THEIR PREPARATION AND USES THEREOF | CENTRE NAT RECH SCIENT (FR) | 2011-10-12 | — | — | EP | disclosed |
| US-8003793-B2 | Methods for making 3-O-protected morphinones and 3-O-protected morphinone dienol carboxylates | PURDUE PHARMA L.P. (US) | 2011-08-23 | — | — | US | disclosed |
| EP-2194059-A2 | Methods for making 3-O-protected morphinones and 3-O-protected morphinone dienol carboxylates | EURO-CELTIQUE S.A. (LU) | 2010-06-09 | — | — | EP | disclosed |
| EP-1864987-B1 | Methods for making 3-O protected morphinones and 3-O-protected morphinone dienol carboxylates | EURO CELTIQUE SA (LU) | 2009-12-09 | — | — | EP | disclosed |
| EP-2035442-A1 | NEW SUPPORTED OXIDATION REACTANTS, PROCESS FOR THEIR PREPARATION AND USES THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2009-03-18 | — | — | EP | disclosed |
| EP-1711502-B1 | METHODS FOR MAKING 3-O-PROTECTED MORPHINONES AND 3-O-PROTECTED MORPHINONE DIENOL CARBOXYLATES | EURO CELTIQUE SA (LU) | 2008-08-27 | — | — | EP | disclosed |
| US-20080146804-A1 | making aldehydes and ketones comprising allowing the corresponding primary or secondary alcohol to react in the presence of trichoroisocyanuric acid, a compound of formula R1SR2 and a base | EURO-CELTIQUE S.A. (LU) | 2008-06-19 | — | — | US | disclosed |
| WO-2007144411-A1 | NEW SUPPORTED OXIDATION REACTANTS, PROCESS FOR THEIR PREPARATION AND USES THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2007-12-21 | — | — | WO | disclosed |
| EP-1864987-A2 | Methods for making 3-O protected morphinones and 3-O-protected morphinone dienol carboxylates | EURO-CELTIQUE S.A. (LU) | 2007-12-12 | — | — | EP | disclosed |
| CN-1918168-A | Methods for making 3-o-protected morphinones and 3-o-protected morphinone dienol carboxylates | EURO CELTIQUE SA (LU) | 2007-02-21 | — | — | CN | disclosed |
| EP-1711502-A2 | METHODS FOR MAKING 3-O-PROTECTED MORPHINONES AND 3-O-PROTECTED MORPHINONE DIENOL CARBOXYLATES | EURO-CELTIQUE S.A. (LU) | 2006-10-18 | — | — | EP | disclosed |
| WO-2005077957-A2 | METHODS FOR MAKING 3-O-PROTECTED MORPHINONES AND 3-O-PROTECTED MORPHINONE DIENOL CARBOXYLATES | EURO-CELTIQUE S.A. (LU) | 2005-08-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080146804-A1 | making aldehydes and ketones comprising allowing the corresponding primary or secondary alcohol to react in the presence of trichoroisocyanuric acid, a compound of formula R1SR2 and a base | ADH1C, TACR2, OGFR | TSHR 177/4885LMNA 4543/4885NFKB1 2737/4885 |
| US-20120022259-A1 | METHODS FOR MAKING 3-O-PROTECTED MORPHINONES AND 3-O-PROTECTED MORPHINONE DIENOL CARBOXYLATES | OGFR, OPRM1, TACR2 | TSHR 127/4885LMNA 3809/4885NFKB1 4054/4885 |
| US-20150239898-A1 | METHODS FOR MAKING 3-O-PROTECTED MORPHINONES AND 3-O-PROTECTED MORPHINONE DIENOL CARBOXYLATES | OGFR, OPRM1, TACR2 | TSHR 127/4885LMNA 3809/4885NFKB1 4054/4885 |
| US-20170233400-A1 | METHODS FOR MAKING 3-O-PROTECTED MORPHINONES AND 3-O-PROTECTED MORPHINONE DIENOL CARBOXYLATES | OGFR, OPRM1, TACR2 | TSHR 131/4885LMNA 3764/4885NFKB1 4044/4885 |
| US-20140171643-A1 | METHODS FOR MAKING 3-O-PROTECTED MORPHINONES AND 3-O-PROTECTED MORPHINONE DIENOL CARBOXYLATES | OGFR, OPRM1, TACR2 | TSHR 127/4885LMNA 3809/4885NFKB1 4054/4885 |
| US-20120225902-A1 | METHODS FOR MAKING 3-O-PROTECTED MORPHINONES AND 3-O-PROTECTED MORPHINONE DIENOL CARBOXYLATES | OGFR, OPRM1, TACR2 | TSHR 127/4885LMNA 3809/4885NFKB1 4054/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.