Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.50 |
| ▸ | PPARG | P37231 | 7/20 | 0.50 |
| ▸ | PPARD | Q03181 | 7/20 | 0.50 |
| ▸ | PPARA | Q07869 | 7/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL426087 | 1.00 | TSHR (0.55) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL15467127 | 0.91 | — | — | |
| SCHEMBL3192362 | 0.89 | PPARG (0.59) | TSHRLMNAPPARGPPARDPPARA | |
| SCHEMBL8592585 | 0.88 | LMNA (0.46) | TSHRLMNANFKB1PMP22GPR84 | |
| Octanedioate SCHEMBL5321589 | 0.85 | TSHR (0.67) | TSHRLMNANFKB1PMP22GPR84 | |
| Adipic Acid SCHEMBL11412900 | 0.83 | LMNA (0.65) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL11401257 | 0.82 | PAOX (0.48) | TSHRLMNANFKB1PMP22ALDH1A1 | |
| SCHEMBL7994585 | 0.82 | PAOX (0.48) | TSHRLMNANFKB1PMP22ALDH1A1 | |
| SCHEMBL9635507 | 0.81 | TSHR (0.60) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL2581538 | 0.81 | TSHR (0.60) | TSHRLMNANFKB1PMP22GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4861436-A | WITH DIMETHYL SULFOXIDE-PELARGONIC ACID EXTRACTIVE AGENT | Berg, Lloyd (US) | 1989-08-29 | — | — | US | claimed |
| EP-1021551-A1 | PLANT FATTY ACID HYDROXYLASE GENES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2000-07-26 | — | — | EP | disclosed |
| WO-1999018224-A1 | PLANT FATTY ACID HYDROXYLASE GENES | THE CENTRE NATIONAL DE RECHERCHE SCIENTIFIQUE (US) | 1999-04-15 | — | — | WO | disclosed |
| US-4861436-A | WITH DIMETHYL SULFOXIDE-PELARGONIC ACID EXTRACTIVE AGENT | Berg, Lloyd (US) | 1989-08-29 | — | — | US | disclosed |