Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.46 |
| ▸ | PPARG | P37231 | 7/20 | 0.46 |
| ▸ | PPARD | Q03181 | 7/20 | 0.46 |
| ▸ | PPARA | Q07869 | 7/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TLR2 | O60603 | 2/20 | 0.46 |
| ▸ | FABP4 | P15090 | 2/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6238997 | 1.00 | TSHR (0.50) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL3677555 | 1.00 | TSHR (0.50) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL28293188 | 1.00 | TSHR (0.50) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL20567296 | 1.00 | TSHR (0.50) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL3672035 | 1.00 | TSHR (0.50) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL28887112 | 1.00 | TSHR (0.50) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL7994715 | 0.98 | LMNA (0.48) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL620276 | 0.91 | LMNA (0.43) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL5705529 | 0.90 | KMT2A (0.52) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL1225161 | 0.89 | LMNA (0.42) | TSHRLMNANFKB1PMP22GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106232719-B | Highly heat-resistant polycarbonate compositions | 沙特基础工业全球技术有限公司 | 2020-05-29 | — | — | CN | disclosed |
| CN-106661218-B | High flow, high heat polycarbonate compositions | 沙特基础工业全球技术有限公司 | 2019-12-27 | — | — | CN | disclosed |
| CN-106536628-B | High flow, high heat polycarbonate compositions | 沙特基础工业全球技术有限公司 | 2019-12-27 | — | — | CN | disclosed |
| WO-2001062752-A1 | PROCESS FOR THE PREPARATION OF GLYCIDYLESTERS OF BRANCHED CARBOXYLIC ACIDS | RESOLUTION RESEARCH NEDERLAND B.V. (NL) | 2001-08-30 | — | — | WO | disclosed |
| US-4772649-A | Polyesteramide and sufficient carbodiimide to impart improved compression set | THE DOW CHEMICAL COMPANY (US) | 1988-09-20 | — | — | US | disclosed |
| EP-0271914-A2 | Polyesteramide with improved compression set | THE DOW CHEMICAL COMPANY (US) | 1988-06-22 | — | — | EP | disclosed |