Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.53 |
| ▸ | MMP1 | P03956 | 5/20 | 0.48 |
| ▸ | MMP9 | P14780 | 5/20 | 0.48 |
| ▸ | MMP13 | P45452 | 5/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
| ▸ | MMP7 | P09237 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.42 |
| ▸ | PRKCG | P05129 | 2/20 | 0.42 |
| ▸ | PRKCB | P05771 | 2/20 | 0.42 |
| ▸ | PRKCA | P17252 | 2/20 | 0.42 |
| ▸ | PRKACA | P17612 | 2/20 | 0.42 |
| ▸ | PRKACG | P22612 | 2/20 | 0.42 |
| ▸ | PRKACB | P22694 | 2/20 | 0.42 |
| ▸ | PRKCH | P24723 | 2/20 | 0.42 |
| ▸ | PRKCI | P41743 | 2/20 | 0.42 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.42 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7980137 | 1.00 | HSD11B1 (0.53) | HSD11B1MMP1MMP9MMP13MMP3 | |
| Hydrochloric Acid SCHEMBL309662 | 0.99 | HSD11B1 (0.52) | HSD11B1MMP1MMP9MMP13MMP3 | |
| Hydrochloric Acid SCHEMBL309881 | 0.99 | HSD11B1 (0.52) | HSD11B1MMP1MMP9MMP13MMP3 | |
| SCHEMBL10042202 | 0.84 | MMP1 (0.65) | HSD11B1MMP1MMP9MMP13MMP3 | |
| SCHEMBL6410896 | 0.83 | HSD11B1 (0.48) | HSD11B1MMP1MMP9MMP13MMP3 | |
| SCHEMBL7991187 | 0.83 | HSD11B1 (0.48) | HSD11B1MMP1MMP9MMP13MMP3 | |
| Hydrochloric Acid SCHEMBL308298 | 0.82 | HSD11B1 (0.47) | HSD11B1MMP1MMP9MMP13MMP3 | |
| Hydrochloric Acid SCHEMBL309182 | 0.82 | HSD11B1 (0.47) | HSD11B1MMP1MMP9MMP13MMP3 | |
| SCHEMBL3718844 | 0.79 | PSEN1 (0.61) | HSD11B1MMP1MMP9MMP13MMP3 | |
| SCHEMBL7892632 | 0.79 | PSEN1 (0.61) | HSD11B1MMP1MMP9MMP13MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010007074-A1 | PYRAZOLO [1, 5-A] PYRIMIDINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2010-01-21 | — | — | WO | disclosed |