Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.82 |
| ▸ | ITGAV | P06756 | 20/20 | 0.82 |
| ▸ | ITGB5 | P18084 | 10/20 | 0.55 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.55 |
| ▸ | ITGB6 | P18564 | 8/20 | 0.54 |
| ▸ | ITGB8 | P26012 | 8/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6423205 | 0.93 | ITGB3 (0.81) | ITGB3ITGAVITGB5ITGB6ITGB8 | |
| SCHEMBL7995239 | 0.90 | ITGB3 (1.00) | ITGB3ITGAVITGB5ITGA2BITGB6 | |
| SCHEMBL7380579 | 0.87 | ITGB3 (0.61) | ITGB3ITGAVITGB5ITGA2BITGB6 | |
| SCHEMBL6420861 | 0.83 | ITGB3 (1.00) | ITGB3ITGAVITGB5ITGB6ITGB8 | |
| SCHEMBL6422671 | 0.83 | ITGB3 (1.00) | ITGB3ITGAVITGB5ITGB6ITGB8 | |
| SCHEMBL6420863 | 0.83 | ITGB3 (1.00) | ITGB3ITGAVITGB5ITGB6ITGB8 | |
| SCHEMBL6105718 | 0.82 | ITGB3 (0.63) | ITGB3ITGAVITGB5ITGA2BITGB6 | |
| SCHEMBL6421100 | 0.82 | ITGB3 (1.00) | ITGB3ITGAVITGB5ITGB6ITGB8 | |
| SCHEMBL6105960 | 0.81 | ITGB3 (0.62) | ITGB3ITGAVITGB5ITGA2BITGB6 | |
| SCHEMBL6424882 | 0.80 | ITGAV (0.60) | ITGB3ITGAVITGB5ITGA2BITGB6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294549-B1 | COMPOUNDS USEFUL FOR INHIBITING RESTENOSIS, ANGIOGENESIS, ATHEROSCLEROSIS, DIABETIC RETINOPATHY, MACULAR DEGENERATION, INFLAMMATION OR TUMOR GROWTH. | MERCK & CO., INC. | 2001-09-25 | — | — | US | disclosed |