Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Furfural. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.50 |
| ▸ | MASP2 | O00187 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | POLB | P06746 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Furfural SCHEMBL15547486 | 0.92 | ALDH1A1 (0.78) | ALDH1A1HCAR2MASP2F2KMT2A | |
| Furfural SCHEMBL17671277 | 0.90 | ALDH1A1 (0.82) | ALDH1A1HCAR2MASP2F2KMT2A | |
| Furfural SCHEMBL28255155 | 0.88 | ALDH1A1 (0.78) | ALDH1A1HCAR2MASP2F2KMT2A | |
| Furfural SCHEMBL11426335 | 0.87 | ALDH1A1 (0.69) | ALDH1A1HCAR2MASP2F2KMT2A | |
| Furfural SCHEMBL2441944 | 0.86 | ALDH1A1 (0.75) | ALDH1A1HCAR2MASP2F2KMT2A | |
| Furfural SCHEMBL19951030 | 0.86 | ALDH1A1 (0.75) | ALDH1A1HCAR2MASP2F2KMT2A | |
| Furfural SCHEMBL27188973 | 0.85 | ALDH1A1 (0.72) | ALDH1A1HCAR2MASP2F2KMT2A | |
| Furfural SCHEMBL6343654 | 0.84 | ALDH1A1 (0.78) | ALDH1A1HCAR2MASP2F2KMT2A | |
| Furfural SCHEMBL653628 | 0.84 | ALDH1A1 (0.78) | ALDH1A1HCAR2MASP2F2KMT2A | |
| Furfural SCHEMBL27941744 | 0.84 | ALDH1A1 (0.78) | ALDH1A1HCAR2MASP2F2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104662074-A | Recycling carbon fibers from epoxy resins using solvent cracking | EMPIRE TECHNOLOGY DEV LLC | 2015-05-27 | — | — | CN | disclosed |
| US-8920932-B2 | Recycling carbon fibers from epoxy using solvent cracking | EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) | 2014-12-30 | — | — | US | disclosed |
| CN-102952570-B | Method for preparing environment-friendly rubber oil by two-stage countercurrent solvent extraction | PETROCHINA CO LTD | 2014-12-24 | — | — | CN | disclosed |
| CN-102952569-B | Method for preparing environment-friendly rubber oil by extraction of ternary composite solvent | PETROCHINA CO LTD | 2014-12-24 | — | — | CN | disclosed |
| CN-102952569-A | Method for preparing environment-friendly rubber oil by extraction of ternary composite solvent | PETROCHINA CO LTD | 2013-03-06 | — | — | CN | disclosed |
| CN-102952570-A | Method for preparing environment-friendly rubber oil by two-stage countercurrent solvent extraction | PETROCHINA CO LTD | 2013-03-06 | — | — | CN | disclosed |
| US-6146520-A | SOLVENT EXTRACTION OF VACUUM DISTILLATES WITH DIMETHYL SULFOXIDE, SULFOLANE, OR PROPYLENE CARBONATE; REMOVAL OF POLYCYCLIC AROMATICS | MOBIL OIL CORPORATION (US) | 2000-11-14 | — | — | US | disclosed |
| EP-0980415-A4 | SELECTIVE RE-EXTRACTION OF LUBE EXTRACTS TO REDUCE MUTAGENICITY INDEX | MOBIL OIL CORP (US) | 2000-06-14 | — | — | EP | disclosed |
| EP-0980415-A1 | SELECTIVE RE-EXTRACTION OF LUBE EXTRACTS TO REDUCE MUTAGENICITY INDEX | ExxonMobil Oil Corporation (US) | 2000-02-23 | — | — | EP | disclosed |
| WO-1998044075-A1 | SELECTIVE RE-EXTRACTION OF LUBE EXTRACTS TO REDUCE MUTAGENICITY INDEX | MOBIL OIL CORPORATION (US) | 1998-10-08 | — | — | WO | disclosed |