Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1D | Q01668 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | SI | P14410 | 1/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.47 |
| ▸ | TARBP2 | Q15633 | 2/20 | 0.44 |
| ▸ | EIF4E | P06730 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | GUSB | P08236 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7978366 | 0.86 | GAA (0.51) | GAAMGAMSIMGAM2EIF4E | |
| SCHEMBL7988441 | 0.83 | AR (0.55) | GAATARBP2ARGABRA2GABRB2 | |
| SCHEMBL7989585 | 0.82 | TARBP2 (0.46) | GAATARBP2GABRA2GABRB2GABRG2 | |
| SCHEMBL7977756 | 0.81 | AR (0.48) | GAAARHSD17B10ALDH1A1 | |
| SCHEMBL7989862 | 0.80 | AR (0.54) | CACNA1DGAATARBP2ARALDH1A1 | |
| SCHEMBL28914603 | 0.80 | AR (0.54) | CACNA1DGAATARBP2ARALDH1A1 | |
| SCHEMBL7992024 | 0.79 | AR (0.58) | GAAARGABRA2GABRB2 | |
| SCHEMBL7988187 | 0.78 | TARBP2 (0.45) | GAATARBP2GABRA2GABRB2GABRG2 | |
| SCHEMBL7988821 | 0.77 | KMT2A (0.52) | GAAMGAMSIMGAM2EIF4E | |
| SCHEMBL7995926 | 0.77 | KDM4E (0.49) | GAATARBP2GABRA2GABRB2GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |