Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MGAM | O43451 | 1/20 | 0.51 |
| ▸ | SI | P14410 | 1/20 | 0.51 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.51 |
| ▸ | EIF4E | P06730 | 6/20 | 0.51 |
| ▸ | GUSB | P08236 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.45 |
| ▸ | CDC7 | O00311 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7995228 | 0.86 | CACNA1D (0.47) | GAAMGAMSIMGAM2EIF4E | |
| SCHEMBL7977380 | 0.81 | MEN1 (0.56) | GAAGUSBMEN1KMT2AALDH1A1 | |
| SCHEMBL7978027 | 0.80 | KDM4E (0.67) | GAAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL7991805 | 0.80 | KDM4E (0.48) | GAAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL7988821 | 0.80 | KMT2A (0.52) | GAAMGAMSIMGAM2EIF4E | |
| SCHEMBL7989916 | 0.76 | IDO1 (0.50) | GAAGUSBMEN1KMT2AALDH1A1 | |
| SCHEMBL7988654 | 0.75 | MMP2 (0.57) | GUSBMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL27987460 | 0.75 | MGAM (0.58) | GAAMGAMSIMGAM2GUSB | |
| SCHEMBL7977763 | 0.74 | CTRC (0.53) | GAAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL7977822 | 0.74 | KDM4E (0.47) | GAAMEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |