Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | CCR3 | P51677 | 2/20 | 0.42 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.42 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989585 | 0.88 | TARBP2 (0.46) | GAARAB9AMAPTLMNAALDH1A1 | |
| SCHEMBL7995767 | 0.88 | KDM4E (0.49) | GAARAB9AMAPTLMNAALDH1A1 | |
| SCHEMBL7977974 | 0.86 | ALOX5 (0.49) | MAPTLMNAALDH1A1HSD17B10ELANE | |
| SCHEMBL7988490 | 0.86 | MAPK14 (0.53) | GAAMAPTLMNAALDH1A1HSD17B10 | |
| SCHEMBL28914603 | 0.86 | AR (0.54) | ARGAARAB9AIDO1MAPT | |
| SCHEMBL7989862 | 0.86 | AR (0.54) | ARGAARAB9AIDO1MAPT | |
| SCHEMBL7992024 | 0.85 | AR (0.58) | ARGAARAB9AMAPTPRKCZ | |
| SCHEMBL7989706 | 0.85 | TARBP2 (0.49) | GAARAB9AMAPTLMNAALDH1A1 | |
| SCHEMBL7989916 | 0.84 | IDO1 (0.50) | GAAIDO1MAPTALDH1A1PSD | |
| SCHEMBL7989869 | 0.83 | KDM4E (0.43) | MAPTLMNAALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |