SCHEMBL7995296

SCHEMBL7995296

CO/C=C(/C(=O)O)c1ccccc1C(=O)/C(=N/OCCc1ccccn1)C1CC1

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.38
MAPK1 P28482 1/20 0.38
TBXA2R P21731 1/20 0.34
CHRM5 P08912 1/20 0.34
CHRM1 P11229 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.33
KDM4E B2RXH2 5/20 0.32
TDP1 Q9NUW8 1/20 0.32
POLB P06746 2/20 0.32
BRD4 O60885 1/20 0.32
CREBBP Q92793 1/20 0.32
GAA P10253 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
THRB P10828 1/20 0.32
F2 P00734 1/20 0.32
CYP1A2 P05177 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7992202 0.82 CHRM5 (0.35) ALDH1A1MAPK1TBXA2RCHRM5CHRM1
SCHEMBL7753085 0.82 CHRM5 (0.35) ALDH1A1MAPK1TBXA2RCHRM5CHRM1
SCHEMBL7753089 0.82 CHRM5 (0.35) ALDH1A1MAPK1TBXA2RCHRM5CHRM1
SCHEMBL7751862 0.77 FKBP1A (0.37) ALDH1A1MAPK1TBXA2RCHRM5CHRM1
SCHEMBL7981403 0.77 FKBP1A (0.37) ALDH1A1MAPK1TBXA2RCHRM5CHRM1
SCHEMBL7752757 0.74 CYP1A2 (0.36) ALDH1A1MAPK1KDM4ETDP1CYP1A2
SCHEMBL7995298 0.73 CYP1A2 (0.35) ALDH1A1TBXA2RCHRM5CHRM1KDM4E
SCHEMBL7993488 0.73 CYP1A2 (0.35) ALDH1A1TBXA2RCHRM5CHRM1KDM4E
SCHEMBL7747858 0.72 PTGIR (0.36) ALDH1A1MAPK1KDM4EPOLBMEN1
SCHEMBL7995305 0.72 KCNA5 (0.35) ALDH1A1TBXA2RCHRM5CHRM1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001023355-A1 NOVEL OPTICALLY ACTIVE FUNGICIDE COMPOUNDS COMPRISING A HYDROXIMIC OR HYDRAZONIC FUNCTION AVENTIS CROPSCIENCE SA (FR) 2001-04-05 WO claimed