SCHEMBL7995305

SCHEMBL7995305

CCC(=NOCCCc1ccccn1)OCc1ccccc1C(=COC)C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KCNA5 P22460 2/20 0.35
KCNK3 O14649 1/20 0.35
KCNA3 P22001 1/20 0.35
CYP1A2 P05177 2/20 0.34
CYP2C19 P33261 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
FKBP1A P62942 1/20 0.34
KDM4E B2RXH2 3/20 0.33
CHRM5 P08912 1/20 0.33
CHRM1 P11229 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
TBXA2R P21731 1/20 0.32
HDAC6 Q9UBN7 4/20 0.32
HDAC1 Q13547 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7993484 0.88 CYP1A2 (0.36) KCNA5KCNK3KCNA3CYP1A2CYP2C19
SCHEMBL7751855 0.82 CYP1A2 (0.34) KCNA5KCNK3KCNA3CYP1A2CYP2C19
SCHEMBL7995299 0.78 ALDH1A1 (0.34) CYP1A2CYP2C19SMN1; SMN2KDM4EALDH1A1
SCHEMBL7993488 0.78 CYP1A2 (0.35) CYP1A2CYP2C19SMN1; SMN2FKBP1AKDM4E
SCHEMBL7995303 0.78 ALDH1A1 (0.34) CYP1A2CYP2C19SMN1; SMN2KDM4EALDH1A1
SCHEMBL7995298 0.78 CYP1A2 (0.35) CYP1A2CYP2C19SMN1; SMN2FKBP1AKDM4E
SCHEMBL7981403 0.77 FKBP1A (0.37) CYP1A2CYP2C19SMN1; SMN2FKBP1AKDM4E
SCHEMBL7751862 0.77 FKBP1A (0.37) CYP1A2CYP2C19SMN1; SMN2FKBP1AKDM4E
SCHEMBL7752757 0.76 CYP1A2 (0.36) KCNA5KCNK3KCNA3CYP1A2KDM4E
SCHEMBL8505441 0.73 HIF1A (0.41) KCNA5ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001023355-A1 NOVEL OPTICALLY ACTIVE FUNGICIDE COMPOUNDS COMPRISING A HYDROXIMIC OR HYDRAZONIC FUNCTION AVENTIS CROPSCIENCE SA (FR) 2001-04-05 WO disclosed