Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 9/20 | 0.62 |
| ▸ | MMP8 | P22894 | 8/20 | 0.62 |
| ▸ | MMP1 | P03956 | 4/20 | 0.62 |
| ▸ | MMP9 | P14780 | 6/20 | 0.57 |
| ▸ | BRS3 | P32247 | 5/20 | 0.57 |
| ▸ | NMBR | P28336 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | MMP7 | P09237 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8000362 | 0.96 | BRS3 (0.61) | MMP2MMP8MMP1MMP9BRS3 | |
| SCHEMBL8000367 | 0.93 | MMP8 (0.67) | MMP2MMP8MMP1MMP9MMP7 | |
| SCHEMBL7998273 | 0.93 | MMP2 (0.57) | MMP2MMP8MMP1MMP9BRS3 | |
| SCHEMBL8000479 | 0.93 | BRS3 (0.65) | MMP2MMP8MMP1MMP9BRS3 | |
| SCHEMBL7998272 | 0.92 | MMP2 (0.56) | MMP2MMP8MMP1MMP9BRS3 | |
| SCHEMBL7997681 | 0.91 | NMBR (0.54) | MMP2MMP8MMP1MMP9BRS3 | |
| SCHEMBL7986870 | 0.90 | BRS3 (0.59) | MMP2MMP8MMP1MMP9BRS3 | |
| SCHEMBL8000344 | 0.89 | BRS3 (0.54) | MMP2MMP8MMP1MMP9BRS3 | |
| SCHEMBL7997643 | 0.89 | MMP8 (0.69) | MMP2MMP8MMP1MMP9BRS3 | |
| SCHEMBL8003758 | 0.88 | NMBR (0.57) | MMP2MMP8MMP1MMP9BRS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009113320-A1 | MMP INHIBITOR | 株式会社ヤクルト本社 (JP) | 2009-09-17 | — | — | WO | disclosed |