Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7994136 | 0.88 | ALOX5AP (0.54) | ALOX5APFEN1 | |
| SCHEMBL7130070 | 0.86 | ALOX5AP (0.55) | ALOX5APFEN1 | |
| SCHEMBL8001453 | 0.85 | ALOX5AP (0.51) | ALOX5APFEN1 | |
| SCHEMBL7994282 | 0.85 | F2 (0.41) | ALOX5APFEN1 | |
| SCHEMBL7994011 | 0.84 | ALOX5AP (0.42) | ALOX5APFEN1 | |
| SCHEMBL7995594 | 0.84 | F10 (0.42) | ALOX5APFEN1 | |
| SCHEMBL7128878 | 0.81 | ALOX5AP (0.53) | ALOX5APFEN1 | |
| SCHEMBL7995553 | 0.79 | ALOX5AP (0.46) | ALOX5APFEN1 | |
| SCHEMBL7995536 | 0.77 | ALOX5AP (0.48) | ALOX5APFEN1 | |
| SCHEMBL890690 | 0.74 | ALOX5AP (0.54) | ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0810858-A4 | BORONIC ACID AND ESTER INHIBITORS OF THROMBIN | DU PONT PHARM CO (US) | 2000-11-15 | — | — | EP | disclosed |
| EP-0810858-A2 | BORONIC ACID AND ESTER INHIBITORS OF THROMBIN | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-12-10 | — | — | EP | disclosed |
| WO-1996020689-A2 | BORONIC ACID AND ESTER INHIBITORS OF THROMBIN | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-07-11 | — | — | WO | disclosed |