Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | MC5R | P33032 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1634791 | 0.88 | PARP1 (0.42) | PARP1HSD17B10SMN1; SMN2NPC1MC4R | |
| SCHEMBL654591 | 0.88 | PARP1 (0.42) | PARP1HSD17B10SMN1; SMN2NPC1MC4R | |
| SCHEMBL6350612 | 0.88 | PARP1 (0.42) | PARP1HSD17B10SMN1; SMN2NPC1MC4R | |
| SCHEMBL18673224 | 0.88 | PARP1 (0.44) | PARP1HSD17B10SMN1; SMN2NPC1MC4R | |
| SCHEMBL28704904 | 0.88 | PARP1 (0.44) | PARP1HSD17B10SMN1; SMN2NPC1MC4R | |
| SCHEMBL2584375 | 0.88 | PARP1 (0.44) | PARP1HSD17B10SMN1; SMN2NPC1MC4R | |
| SCHEMBL2480835 | 0.88 | HSD17B10 (0.47) | PARP1HSD17B10SMN1; SMN2NPC1MC4R | |
| SCHEMBL2480988 | 0.88 | HSD17B10 (0.47) | PARP1HSD17B10SMN1; SMN2NPC1MC4R | |
| SCHEMBL1685922 | 0.88 | HSD17B10 (0.47) | PARP1HSD17B10SMN1; SMN2NPC1MC4R | |
| Ammonia Solution, Strong SCHEMBL22169218 | 0.87 | PARP1 (0.42) | PARP1HSD17B10SMN1; SMN2NPC1MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6297375-B1 | 4-phenyl-pyridine derivatives | HOFFMANN-LA ROCHE INC. | 2001-10-02 | — | — | US | disclosed |