SCHEMBL2480835

SCHEMBL2480835

CC(C)(C)OC(=O)N1CCNCC1C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.47
PARP1 P09874 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.41
NPC1 O15118 1/20 0.36
MC4R P32245 1/20 0.36
MC5R P33032 1/20 0.36
USP2 O75604 1/20 0.36
MAPK1 P28482 1/20 0.35
LMNA P02545 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
CHRM2 P08172 1/20 0.34
CHRM1 P11229 1/20 0.34
CHRM3 P20309 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2480988 1.00 HSD17B10 (0.47) HSD17B10PARP1SMN1; SMN2NPC1MC4R
SCHEMBL1685922 1.00 HSD17B10 (0.47) HSD17B10PARP1SMN1; SMN2NPC1MC4R
Piperazine SCHEMBL28831394 0.97 HSD17B10 (0.45) HSD17B10PARP1SMN1; SMN2NPC1MC4R
Piperazine SCHEMBL28831395 0.97 HSD17B10 (0.45) HSD17B10PARP1SMN1; SMN2NPC1MC4R
SCHEMBL7995550 0.88 PARP1 (0.44) HSD17B10PARP1SMN1; SMN2NPC1MC4R
SCHEMBL2584375 0.88 PARP1 (0.44) HSD17B10PARP1SMN1; SMN2NPC1MC4R
SCHEMBL18673224 0.88 PARP1 (0.44) HSD17B10PARP1SMN1; SMN2NPC1MC4R
SCHEMBL28704904 0.88 PARP1 (0.44) HSD17B10PARP1SMN1; SMN2NPC1MC4R
SCHEMBL15402543 0.86 PARP1 (0.43) HSD17B10PARP1SMN1; SMN2NPC1MC4R
SCHEMBL17560433 0.86 PARP1 (0.43) HSD17B10PARP1SMN1; SMN2NPC1MC4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104046246-B The chemical-mechanical planarization of tungsten-containing substrate 气体产品与化学公司 2016-06-15 CN claimed
US-20140273458-A1 Chemical Mechanical Planarization for Tungsten-Containing Substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-18 US claimed
EP-2779217-A2 Chemical mechanical planarization for tungsten-containing substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-17 EP claimed
CN-104046246-A Chemical Mechanical Planarization for Tungsten-Containing Substrates AIR PROD & CHEM 2014-09-17 CN claimed
EP-4637926-A1 SYNTHESIS, PHARMACOLOGY AND USE OF NEW WATER-SOLUBLE AND SELECTIVE FMS-LIKE TYROSINE KINASE 3 (FLT3) INHIBITORS Universität Regensburg (DE) 2025-10-29 EP disclosed
US-12441735-B2 Nitrogen-containing heterocyclic compound having NRF2 activation effect CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-10-14 US disclosed
US-20250236593-A1 SMALL MOLECULES THAT SENSITIZE HIV-1 INFECTED CELLS TO ANTIBODY DEPENDENT CELLULAR CYTOTOXICITY UNIV PENNSYLVANIA (US) 2025-07-24 US disclosed
US-20250171457-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HAVING NRF2 ACTIVATION EFFECT CHUGAI PHARMACEUTICAL CO LTD (JP) 2025-05-29 US disclosed
US-12286434-B2 Pan-tropic entry inhibitors EMORY UNIVERSITY (US) 2025-04-29 US disclosed
US-12286401-B2 Small molecules that sensitize HIV-1 infected cells to antibody dependent cellular cytotoxicity THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2025-04-29 US disclosed
US-20250084093-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HAVING NRF2 ACTIVATION EFFECT CHUGAI PHARMACEUTICAL CO LTD (JP) 2025-03-13 US disclosed
CN-119431317-A Cyanuric chloride trisubstituted amine derivative as antiviral, preparation method and application thereof 中国科学院上海药物研究所 2025-02-14 CN disclosed
EP-1037905-A1 ANTIPICORNAVIRAL COMPOUNDS AND METHODS FOR THEIR USE AND PREPARATION AGOURON PHARMACEUTICALS, INC. (US) 2000-09-27 EP disclosed
CN-1052231-C Adhesion receptor antagonists MERCK PATENT GMBH (DE) 2000-05-10 CN disclosed
US-5962487-A PICORNAVIRAL 3C PROTEASE INHIBITORS AGOURON PHARMACEUTICALS, INC. (US) 1999-10-05 US disclosed
WO-1999031122-A9 ANTIPICORNAVIRAL COMPOUNDS AND METHODS FOR THEIR USE AND PREPARATION AGOURON PHARMA (US) 1999-09-30 WO disclosed
WO-1999031122-A1 ANTIPICORNAVIRAL COMPOUNDS AND METHODS FOR THEIR USE AND PREPARATION AGOURON PHARMACEUTICALS, INC. (US) 1999-06-24 WO disclosed
CN-1097421-A Adhesion receptor antagonists MERCK PATENT GMBH (DE) 1995-01-18 CN disclosed
WO-1995000498-A1 N,N-DIACYLPIPERAZINES MERCK & CO., INC. (US) 1995-01-05 WO disclosed
US-5348955-A Angiotensis II antagonists MERCK & CO., INC. (US) 1994-09-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250236593-A1 SMALL MOLECULES THAT SENSITIZE HIV-1 INFECTED CELLS TO ANTIBODY DEPENDENT CELLULAR CYTOTOXICITY CD4, NFATC1, GZMB HSD17B10 4288/4885PARP1 557/4885SMN1; SMN2 3435/4885
US-12441735-B2 Nitrogen-containing heterocyclic compound having NRF2 activation effect KEAP1, NFE2L2, BACH1 HSD17B10 1500/4885PARP1 1598/4885SMN1; SMN2 1337/4885
US-12286401-B2 Small molecules that sensitize HIV-1 infected cells to antibody dependent cellular cytotoxicity CD4, NFATC1, GZMB HSD17B10 4288/4885PARP1 557/4885SMN1; SMN2 3435/4885
US-12286434-B2 Pan-tropic entry inhibitors CXCR4, CCR5, CXCL12 HSD17B10 4000/4885PARP1 630/4885SMN1; SMN2 2765/4885
US-20250171457-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HAVING NRF2 ACTIVATION EFFECT KEAP1, NFE2L2, BACH1 HSD17B10 1500/4885PARP1 1598/4885SMN1; SMN2 1337/4885
US-20250084093-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HAVING NRF2 ACTIVATION EFFECT KEAP1, NFE2L2, BACH1 HSD17B10 1559/4885PARP1 1716/4885SMN1; SMN2 1349/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.