Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 5/20 | 0.50 |
| ▸ | PELI1 | Q96FA3 | 2/20 | 0.49 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | PTPRS | Q13332 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18002228 | 0.77 | ERN1 (0.51) | ERN1ACMSDCYP2A6PTPRC | |
| SCHEMBL12060965 | 0.74 | ERN1 (0.49) | ERN1PELI1TMIGD3ADORA2AADORA1 | |
| SCHEMBL9472211 | 0.73 | PTPN1 (0.53) | PELI1ALOX5CYP2A6 | |
| SCHEMBL29431673 | 0.73 | TMIGD3 (0.48) | ERN1PELI1TMIGD3ADORA2AADORA1 | |
| SCHEMBL7533951 | 0.72 | ERN1 (0.51) | ERN1PELI1TMIGD3ADORA2AADORA1 | |
| SCHEMBL6742709 | 0.72 | ALDH1A1 (0.53) | ERN1PELI1MAOB | |
| SCHEMBL7575275 | 0.72 | PELI1 (0.40) | ERN1PELI1ADORA2AADORA1MAOB | |
| SCHEMBL2548779 | 0.71 | ERN1 (0.53) | ERN1ACMSDCYP2A6PTPRC | |
| SCHEMBL609426 | 0.70 | ERN1 (0.49) | ERN1PELI1MAOBCYP2A6PTPRC | |
| SCHEMBL18002215 | 0.70 | CYP2A6 (0.49) | ERN1ACMSDCYP2A6PTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6063815-A | TREATMENT OF METABOLIC DISORDERS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-05-16 | — | — | US | disclosed |