Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 8/20 | 0.41 |
| ▸ | HSP90B1 | P14625 | 8/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7994293 | 0.90 | NPC1 (0.42) | HSP90AA1HSP90B1ADRA2CRAB9ALMNA | |
| SCHEMBL7998777 | 0.86 | GRM2 (0.45) | HSP90AA1HSP90B1GRM2ADRA2CRAB9A | |
| SCHEMBL7998204 | 0.86 | GRM2 (0.41) | HSP90AA1HSP90B1GRM2RAB9ALMNA | |
| SCHEMBL7984007 | 0.83 | HSP90AA1 (0.38) | HSP90AA1HSP90B1ADRA2CLMNAKCNH2 | |
| SCHEMBL8001628 | 0.83 | GRM2 (0.41) | GRM2RAB9ANPC1 | |
| SCHEMBL7997836 | 0.82 | TP53 (0.41) | HSP90AA1HSP90B1LMNAKCNH2SMN1; SMN2 | |
| SCHEMBL7994228 | 0.80 | SMN1; SMN2 (0.48) | GRM2RAB9ALMNANPC1SMN1; SMN2 | |
| SCHEMBL7994645 | 0.78 | HSP90AA1 (0.34) | HSP90AA1HSP90B1RAB9A | |
| SCHEMBL7994182 | 0.76 | KMT2A (0.40) | GRM2RAB9ALMNAKCNH2NPC1 | |
| SCHEMBL7996140 | 0.72 | KMT2A (0.39) | HSP90AA1HSP90B1RAB9ALMNAKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | claimed |
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |