Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984159 | 0.90 | EGFR (0.31) | — | |
| SCHEMBL7996545 | 0.88 | CYP2D6 (0.36) | — | |
| SCHEMBL7998616 | 0.82 | SMN1; SMN2 (0.39) | MAPTHTTRAB9A | |
| SCHEMBL7994819 | 0.80 | — | — | |
| SCHEMBL7995706 | 0.78 | HSP90AA1 (0.41) | HSP90AA1HSP90B1RAB9A | |
| SCHEMBL7994815 | 0.78 | TDP1 (0.31) | — | |
| SCHEMBL7994293 | 0.76 | NPC1 (0.42) | HSP90AA1HSP90B1MAPTHTTRAB9A | |
| SCHEMBL8081077 | 0.75 | CYP1A2 (0.33) | — | |
| SCHEMBL8001628 | 0.74 | GRM2 (0.41) | HTTRAB9A | |
| SCHEMBL7984007 | 0.73 | HSP90AA1 (0.38) | HSP90AA1HSP90B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | claimed |
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |