Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.62 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29434678 | 0.82 | HTR2A (0.42) | HTR2ACA1CA2TNKS2KMT2A | |
| SCHEMBL1402081 | 0.78 | HTR2A (1.00) | HTR2ARETHTR2CHRH1CA1 | |
| SCHEMBL29902960 | 0.78 | HTR2A (1.00) | HTR2ARETHTR2CHRH1CA1 | |
| SCHEMBL22770492 | 0.77 | HTR2A (0.39) | HTR2ATNKS2KMT2ANPC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3895426 | 0.76 | HTR2A (0.95) | HTR2ARETHTR2CHRH1CA1 | |
| SCHEMBL6992701 | 0.75 | HTR2A (0.66) | HTR2ARETHTR2CHRH1 | |
| SCHEMBL6997509 | 0.75 | HTR2A (0.66) | HTR2ARETHTR2CHRH1 | |
| SCHEMBL19139194 | 0.72 | GPR3 (0.38) | HTR2ATNKS2KMT2A | |
| SCHEMBL3802354 | 0.72 | ALDH1A1 (0.39) | TNKS2KMT2AALDH1A1MAPTRAB9A | |
| Formic Acid SCHEMBL28617966 | 0.68 | HTR2A (0.76) | HTR2ARETHTR2CHRH1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277851-B1 | ORALLY ADMINISTERED TRYPSIN-RELATED SERINE PROTEASE INHIBITORS; ANTICOAGULANTS | ADIR ET COMPAGNIE (FR) | 2001-08-21 | — | — | US | disclosed |