Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 12/20 | 0.48 |
| ▸ | PSEN1 | P49768 | 8/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 8/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 8/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 8/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 8/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 8/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21066906 | 1.00 | CCR2 (0.48) | CCR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL7135998 | 1.00 | CCR2 (0.48) | CCR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5959020 | 0.95 | CCR2 (0.42) | CCR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL15855802 | 0.90 | CCR2 (0.36) | CCR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL7247355 | 0.90 | CCR2 (0.36) | CCR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2530439 | 0.80 | L3MBTL1 (0.36) | CCR2 | |
| SCHEMBL12494295 | 0.80 | PSEN1 (0.44) | CCR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL27703589 | 0.77 | CCR2 (0.41) | CCR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL27706673 | 0.77 | CCR2 (0.41) | CCR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL4188392 | 0.76 | L3MBTL1 (0.44) | CCR2PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6297233-B1 | Lactam inhibitors of FXa and method | BRISTOL-MYERS SQUIBB COMPANY | 2001-10-02 | — | — | US | disclosed |