Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | ASIC1 | P78348 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | PDE4A | P27815 | 1/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.53 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GALR3 | O60755 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23297368 | 0.83 | PDE4B (0.71) | MAPTADORA2AL3MBTL1PDE4APDE4B | |
| SCHEMBL7726116 | 0.82 | ADORA2A (0.61) | MAPTADORA2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13734555 | 0.82 | MAPT (0.56) | MAPTADORA2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7996514 | 0.81 | SMN1; SMN2 (0.56) | MAPTSMN1; SMN2TP53MDM2MEN1 | |
| SCHEMBL19924937 | 0.81 | SMN1; SMN2 (0.74) | MAPTADORA2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7723670 | 0.80 | MAPT (0.63) | MAPTADORA2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL14973090 | 0.79 | MAPT (0.53) | MAPTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7720271 | 0.78 | MAPT (0.64) | MAPTADORA2ANPC1RAB9APDE4A | |
| SCHEMBL7724840 | 0.78 | MAPT (0.61) | MAPTADORA2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3841611 | 0.78 | MAPT (0.70) | MAPTL3MBTL1PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000019994-A9 | ESTROGEN RECEPTOR LIGANDS | UNIV ILLINOIS (US) | 2000-08-31 | — | — | WO | disclosed |
| WO-2000019994-A1 | ESTROGEN RECEPTOR LIGANDS | BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2000-04-13 | — | — | WO | disclosed |