Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | STAT3 | P40763 | 2/20 | 0.54 |
| ▸ | GALR3 | O60755 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | NPY1R | P25929 | 1/20 | 0.54 |
| ▸ | NPY2R | P49146 | 1/20 | 0.54 |
| ▸ | MGLL | Q99685 | 2/20 | 0.51 |
| ▸ | ESR1 | P03372 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.47 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.47 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.46 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.46 |
| ▸ | MARS1 | P56192 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5221734 | 0.88 | MTOR (0.46) | SMN1; SMN2MAPTMEN1KMT2ASTAT3 | |
| SCHEMBL3631457 | 0.81 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPTMEN1KMT2ASTAT3 | |
| SCHEMBL7995817 | 0.81 | MAPT (0.63) | SMN1; SMN2MAPTMEN1KMT2ASTAT3 | |
| SCHEMBL7041015 | 0.79 | SMN1; SMN2 (0.66) | SMN1; SMN2MAPTMEN1KMT2ASTAT3 | |
| SCHEMBL3858531 | 0.76 | POLB (0.69) | SMN1; SMN2MAPTMEN1KMT2APOLB | |
| SCHEMBL17853353 | 0.75 | POLB (0.71) | SMN1; SMN2MAPTMEN1KMT2ASTAT3 | |
| SCHEMBL26980565 | 0.75 | SMN1; SMN2 (0.52) | SMN1; SMN2MAPTMEN1KMT2ASTAT3 | |
| SCHEMBL17279807 | 0.74 | ESRRA (0.58) | MAPTMEN1KMT2ASTAT3POLB | |
| SCHEMBL8011425 | 0.74 | MGLL (0.53) | SMN1; SMN2MAPTMEN1KMT2AMGLL | |
| SCHEMBL17279999 | 0.73 | SMN1; SMN2 (0.50) | SMN1; SMN2MAPTMEN1KMT2ASTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000019994-A9 | ESTROGEN RECEPTOR LIGANDS | UNIV ILLINOIS (US) | 2000-08-31 | — | — | WO | disclosed |
| WO-2000019994-A1 | ESTROGEN RECEPTOR LIGANDS | BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2000-04-13 | — | — | WO | disclosed |