SCHEMBL7995850

SCHEMBL7995850

CCCCc1ncc(C=O)n1Cc1ccc(CC(=O)OC)cc1

nearest known ligand 0.55

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 8/20 0.52
AGTR2 P50052 3/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL946900 0.87 AGTR1 (0.67) AGTR1AGTR2
SCHEMBL9128117 0.83 AGTR1 (0.49) AGTR1AGTR2
SCHEMBL8193124 0.83 AGTR1 (0.49) AGTR1AGTR2
SCHEMBL9128122 0.83 AGTR1 (0.54) AGTR1AGTR2
SCHEMBL951175 0.83 AGTR1 (0.66) AGTR1AGTR2
SCHEMBL8507705 0.81 AGTR1 (0.56) AGTR1AGTR2
SCHEMBL8260760 0.81 AGTR1 (0.48) AGTR1AGTR2
SCHEMBL27406325 0.81 AGTR1 (0.55) AGTR1AGTR2
SCHEMBL9165250 0.80 AGTR1 (0.72) AGTR1AGTR2
SCHEMBL9120388 0.80 AGTR1 (0.50) AGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100137613-A1 PROCESS FOR EPROSARTAN HETERO DRUGS LIMITED (IN) 2010-06-03 US disclosed
WO-2009122421-A2 IMPROVED PROCESS FOR EPROSARTAN INTERMEDIATE HETERO RESEARCH FOUNDATION (IN) 2009-10-08 WO disclosed
WO-2008078330-A1 IMPROVED PROCESS FOR EPROSARTAN HETERO DRUGS LIMITED (IN) 2008-07-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100137613-A1 PROCESS FOR EPROSARTAN PTMA, PTGER1, PDGFRA AGTR1 289/4885AGTR2 213/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.