Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 20/20 | 0.69 |
| ▸ | HTR2A | P28223 | 18/20 | 0.69 |
| ▸ | HTR2B | P41595 | 5/20 | 0.56 |
| ▸ | HTR1A | P08908 | 2/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.56 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.56 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.56 |
| ▸ | HTR1D | P28221 | 1/20 | 0.56 |
| ▸ | HTR7 | P34969 | 1/20 | 0.56 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7998321 | 1.00 | HTR2C (0.69) | HTR2CHTR2AHTR2BHTR1AADRA2A | |
| SCHEMBL7092848 | 1.00 | HTR2C (0.69) | HTR2CHTR2AHTR2BHTR1AADRA2A | |
| Fumaric Acid SCHEMBL7091553 | 0.89 | HTR2C (0.57) | HTR2CHTR2AHTR2BHTR1AADRA2A | |
| Fumaric Acid SCHEMBL7091552 | 0.89 | HTR2C (0.57) | HTR2CHTR2AHTR2BHTR1AADRA2A | |
| SCHEMBL8001801 | 0.88 | HTR2C (0.67) | HTR2CHTR2AHTR2BHTR1AADRA2A | |
| SCHEMBL8001799 | 0.88 | HTR2C (0.67) | HTR2CHTR2AHTR2BHTR1AADRA2A | |
| SCHEMBL9230485 | 0.82 | HTR2C (1.00) | HTR2CHTR2AHTR2BHTR7CYP1A2 | |
| SCHEMBL9230483 | 0.82 | HTR2C (1.00) | HTR2CHTR2AHTR2BHTR7CYP1A2 | |
| SCHEMBL7997689 | 0.81 | HTR2C (0.77) | HTR2CHTR2AHTR2BHTR7CYP1A2 | |
| SCHEMBL8959602 | 0.81 | HTR2C (1.00) | HTR2CHTR2AHTR2BCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001040183-A1 | 1-AMINOALKYL-1H-INDOLES FOR TREATING GLAUCOMA | ALCON UNIVERSAL LTD. (CH) | 2001-06-07 | — | — | WO | disclosed |