Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.61 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.56 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4263728 | 0.98 | PKM (0.64) | PKMLMNANOTUMGAAPTK2 | |
| SCHEMBL10768177 | 0.87 | PKM (0.78) | PKMLMNANOTUMGAAPTK2 | |
| SCHEMBL15013310 | 0.81 | LMNA (0.64) | PKMLMNANOTUMGAAPTK2 | |
| SCHEMBL19219054 | 0.81 | PTK2 (0.91) | PKMLMNANOTUMGAAPTK2 | |
| SCHEMBL6608660 | 0.79 | GAA (0.96) | PKMLMNANOTUMGAAPTK2 | |
| SCHEMBL6606173 | 0.78 | PKM (0.60) | PKMLMNANOTUMGAAPTK2 | |
| SCHEMBL16159857 | 0.78 | CYP11B1 (0.73) | PKMLMNANOTUMGAAPTK2 | |
| SCHEMBL472353 | 0.77 | NOTUM (1.00) | PKMLMNANOTUMGAAPTK2 | |
| SCHEMBL3299412 | 0.77 | PKM (0.64) | PKMLMNANOTUMGAAPTK2 | |
| SCHEMBL3635051 | 0.77 | PKM (0.64) | PKMLMNANOTUMGAAPTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000019994-A9 | ESTROGEN RECEPTOR LIGANDS | UNIV ILLINOIS (US) | 2000-08-31 | — | — | WO | disclosed |
| WO-2000019994-A1 | ESTROGEN RECEPTOR LIGANDS | BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2000-04-13 | — | — | WO | disclosed |